Block 7 CAT
نویسنده
چکیده
Introduction: Though endotracheal intubation is considered the gold standard for airway control, direct laryngoscopy ET insertion is highly operator-dependent. Given that we have access to other types of airway devices, such as the 1 st gen LMA, King-LTS airway (laryngeal tube suction), and supreme laryngeal mask airway (SLMA), this study looked at how they compare to each other with regard to successful airway control, number of attempts required, and time to achieve airway control.
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Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy
INTRODUCTION Hypertrophic cardiomyopathy (HCM) is a cause of sudden arrhythmic death, but the understanding of its pro-arrhythmic mechanisms and an effective pharmacological treatment are lacking. HCM electrophysiological remodelling includes both increased inward and reduced outward currents, but their role in promoting repolarisation abnormalities remains unknown. The goal of this study is to...
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Block of the delayed rectifier potassium current, IK, by the class IC antiarrhythmic agent, flecainide, and by the novel selective class III antiarrhythmic agent, E-4031, were compared in isolated cat ventricular myocytes using the single suction-pipette, voltage-clamp technique. Flecainide (10 microM) markedly reduced IK elicited on depolarization steps to plateau voltages (+10 mV) and nearly ...
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Block of the delayed rectifier potassium current, IK, by the class IC antiarrhythmic agent, flecainide, and by the novel selective class III antiarrhythmic agent, E-4031, were compared in isolated cat ventricular myocytes using the single suction-pipette, voltage-clamp technique. Flecainide (10 jiM) markedly reduced IK elicited on depolarization steps to plateau voltages (+10 mV) and nearly com...
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